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Important safety information
Important Safety Information for Ozempic (semaglutide) injection
Caution: Risk of Thyroid C-Cell Tumors
In animal studies involving mice and rats, semaglutide (the active component in Ozempic and Wegovy) was associated with thyroid tumors, including thyroid cancer. It is uncertain whether Ozempic may lead to thyroid tumors or a specific thyroid cancer called medullary thyroid carcinoma (MTC) in humans. If you notice any neck lumps, swelling, hoarseness, difficulty swallowing, or shortness of breath, please inform your healthcare provider. These could be signs of thyroid cancer.
Do not use Ozempic if you or any family member has a history of medullary thyroid carcinoma (MTC) or a condition known as Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
What is the FDA-approved use of Ozempic?
Ozempic is a glucagon-like peptide-1 (GLP-1) receptor agonist used for:
- Enhancing glycemic control in patients with type 2 diabetes mellitus, alongside diet and exercise.
- Reducing the risk of major cardiovascular events in patients with type 2 diabetes mellitus and established cardiovascular disease.
Limitations of Use:
- Ozempic has not been studied in patients with a history of pancreatitis.
- Ozempic is not intended for treating type 1 diabetes mellitus.
- Your JRNYS-affiliated provider may suggest Ozempic for chronic weight management (obesity or overweight).
Who should avoid Ozempic?
Do not use Ozempic if:
- You or any family member has a history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
- You have known allergies to semaglutide (the active ingredient in Wegovy or Ozempic).
How should Ozempic be administered?
Ozempic can be taken with or without food. The pre-filled injector pen is self-administered as a subcutaneous injection in the stomach, thigh, or upper arm once a week on the same day each week.
Your JRNYS-affiliated provider will guide you on the treatment plan, which may include dose increases every four weeks.
Do not alter your dosing regimen or discontinue Ozempic without consulting your provider first.
What should I inform my JRNYS-affiliated provider before using Ozempic?
Ozempic can interact with certain medications. It's crucial to disclose all current medications, including prescription, over-the-counter drugs, vitamins, herbal supplements, and dietary supplements to your JRNYS-affiliated provider.
Some medications to be aware of include:
- Drugs for type 1 or type 2 diabetes, such as insulin or sulfonylureas (e.g., Amaryl or Glucotrol XL).
- Ozempic can delay gastric emptying, potentially affecting the absorption of orally taken medications. Your provider can advise on scheduling your medications.
Additionally, share your complete medical history with your provider, especially if you have a history of:
- Type 1 or type 2 diabetes
- Thyroid cancer
- Pancreatitis
- Kidney disease
- Diabetic retinopathy
- Depression
- Suicidal thoughts or behavior
Notify your provider if you are pregnant, planning to become pregnant, or breastfeeding.
If pregnant: Ozempic should not be used during pregnancy. Animal studies suggest potential risks to the unborn baby from Ozempic exposure during pregnancy. Weight loss during pregnancy is not beneficial and may harm the baby.
If of reproductive potential: Discontinue Ozempic at least two months before planned pregnancy, as the drug may persist in the bloodstream.
If breastfeeding: Ozempic was detected in the milk of lactating rats. Inform your JRNYS-affiliated provider if you are breastfeeding before starting Ozempic.
Pregnancy registry: A pregnancy exposure registry monitors outcomes in women exposed to semaglutide (the active ingredient in Ozempic and Ozempic) during pregnancy.
Pregnant women exposed to semaglutide and healthcare providers can contact Novo Nordisk at 1-800-727-6500.
Withholding or providing inaccurate health information to obtain treatment may lead to harm, including death.
What are the most serious side effects to monitor for while taking Ozempic?
If you experience a medical emergency, call 911 or seek immediate medical attention.
Serious side effects associated with Ozempic include:
- Thyroid C-Cell Tumors: While Ozempic's impact on human thyroid C-cell tumors remains uncertain, animal studies revealed an increase in thyroid C-cell tumors, including MTC. Ozempic is contraindicated for patients with a family history of MTC or MEN 2. Notify your provider if you notice neck lumps, swelling, hoarseness, difficulty swallowing, or shortness of breath, as these may indicate thyroid cancer.
- Acute Pancreatitis: Be vigilant for signs of acute pancreatitis, such as persistent severe abdominal pain, possibly radiating to the back, with or without vomiting.
- Diabetic Retinopathy Complications in Patients with Type 2 Diabetes: If you have type 2 diabetes, promptly inform your provider of any changes in vision.
- Never Share a Pen: Sharing Ozempic pens can lead to infections.
- Low Blood Sugar (Hypoglycemia): Ozempic can lower blood glucose, potentially causing low blood sugar in patients with type 2 diabetes using other glucose control medications. Monitor blood sugar levels and watch for signs of low blood sugar, including dizziness, blurred vision, mood changes, sweating, or rapid heartbeat.
- Acute Kidney Injury: In individuals with kidney issues, dehydration from diarrhea, nausea, and vomiting can worsen kidney problems. Ensure adequate hydration to reduce the risk of dehydration.
- Serious Allergic Reactions: Discontinue Ozempic immediately if you experience symptoms of a severe allergic reaction, such as facial swelling, severe rash, rapid heartbeat, breathing difficulties, or fainting.
- Acute Gallbladder Disease: Ozempic may lead to gallbladder problems, including gallstones. Some issues may require surgery. Inform your provider of upper stomach pain, yellowing of skin or eyes (jaundice), fever, or pale stools.
- Increase in Heart Rate: Notify your provider of a rapid resting heart rate.
- Suicidal Behavior and Ideation: Monitor your mental health for sudden changes in mood, behavior, thoughts, or feelings. If you experience new, worsening, or concerning mental changes, contact your healthcare provider promptly.
What are the most common side effects of Ozempic?
Common side effects of Ozempic include:
- Nausea
- Vomiting
- Diarrhea
- Stomach pain
- Constipation
If you experience adverse effects, please report them:
- Contact Novo Nordisk Inc. at 1-833-934-6891
- Contact FDA MedWatch at 1-800-FDA-1088 or visit www.fda.gov/medwatch
This information is not exhaustive. Refer to the full Prescribing Information for complete safety details.
Semaglutide
- Lowers A1C Levels
- Helps you feel full faster, longer
- Improves the way your body responds to sugars
- Semaglutide is not FDA-approved for weight loss, but may be prescribed if a provider deems it appropriate*
- 24/7 Provider & Nursing support
- Medications, syringes, alcohol swabs
- Weight monitoring via app
- Shipping delivered to your door
- Optional nutritional counseling
Semaglutide is typically administered as a once-weekly subcutaneous injection, meaning it is injected just under the skin, usually in the abdomen, thigh, or upper arm. It's important to rotate the injection site each week to avoid irritation. Always follow the dosing instructions provided by your healthcare provider, starting with a lower dose and gradually increasing based on your body's response. Be sure to use a clean needle for each injection and dispose of it safely. If you miss a dose, take it as soon as you remember, unless it's less than 48 hours before your next scheduled dose. Never double up on doses. For optimal results, use semaglutide in combination with a healthy diet and regular exercise
Common side effects of semaglutide may include nausea, vomiting, diarrhea, constipation, and abdominal pain, especially when starting treatment. Other possible side effects include fatigue, dizziness, and decreased appetite. In rare cases, semaglutide can cause more serious side effects like pancreatitis, gallbladder issues, or allergic reactions. If you experience severe abdominal pain, difficulty breathing, or swelling of the face or throat, seek medical attention immediately. Always consult your healthcare provider about any side effects or concerns you may have.
* This page has been medically reviewed
* Actual price to customer will depend on product and subscription plan purchase.
Important safety information
Important Safety Information for Ozempic (semaglutide) injection
Caution: Risk of Thyroid C-Cell Tumors
In animal studies involving mice and rats, semaglutide (the active component in Ozempic and Wegovy) was associated with thyroid tumors, including thyroid cancer. It is uncertain whether Ozempic may lead to thyroid tumors or a specific thyroid cancer called medullary thyroid carcinoma (MTC) in humans. If you notice any neck lumps, swelling, hoarseness, difficulty swallowing, or shortness of breath, please inform your healthcare provider. These could be signs of thyroid cancer.
Do not use Ozempic if you or any family member has a history of medullary thyroid carcinoma (MTC) or a condition known as Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
What is the FDA-approved use of Ozempic?
Ozempic is a glucagon-like peptide-1 (GLP-1) receptor agonist used for:
- Enhancing glycemic control in patients with type 2 diabetes mellitus, alongside diet and exercise.
- Reducing the risk of major cardiovascular events in patients with type 2 diabetes mellitus and established cardiovascular disease.
Limitations of Use:
- Ozempic has not been studied in patients with a history of pancreatitis.
- Ozempic is not intended for treating type 1 diabetes mellitus.
- Your JRNYS-affiliated provider may suggest Ozempic for chronic weight management (obesity or overweight).
Who should avoid Ozempic?
Do not use Ozempic if:
- You or any family member has a history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
- You have known allergies to semaglutide (the active ingredient in Wegovy or Ozempic).
How should Ozempic be administered?
Ozempic can be taken with or without food. The pre-filled injector pen is self-administered as a subcutaneous injection in the stomach, thigh, or upper arm once a week on the same day each week.
Your JRNYS-affiliated provider will guide you on the treatment plan, which may include dose increases every four weeks.
Do not alter your dosing regimen or discontinue Ozempic without consulting your provider first.
What should I inform my JRNYS-affiliated provider before using Ozempic?
Ozempic can interact with certain medications. It's crucial to disclose all current medications, including prescription, over-the-counter drugs, vitamins, herbal supplements, and dietary supplements to your JRNYS-affiliated provider.
Some medications to be aware of include:
- Drugs for type 1 or type 2 diabetes, such as insulin or sulfonylureas (e.g., Amaryl or Glucotrol XL).
- Ozempic can delay gastric emptying, potentially affecting the absorption of orally taken medications. Your provider can advise on scheduling your medications.
Additionally, share your complete medical history with your provider, especially if you have a history of:
- Type 1 or type 2 diabetes
- Thyroid cancer
- Pancreatitis
- Kidney disease
- Diabetic retinopathy
- Depression
- Suicidal thoughts or behavior
Notify your provider if you are pregnant, planning to become pregnant, or breastfeeding.
If pregnant: Ozempic should not be used during pregnancy. Animal studies suggest potential risks to the unborn baby from Ozempic exposure during pregnancy. Weight loss during pregnancy is not beneficial and may harm the baby.
If of reproductive potential: Discontinue Ozempic at least two months before planned pregnancy, as the drug may persist in the bloodstream.
If breastfeeding: Ozempic was detected in the milk of lactating rats. Inform your JRNYS-affiliated provider if you are breastfeeding before starting Ozempic.
Pregnancy registry: A pregnancy exposure registry monitors outcomes in women exposed to semaglutide (the active ingredient in Ozempic and Ozempic) during pregnancy.
Pregnant women exposed to semaglutide and healthcare providers can contact Novo Nordisk at 1-800-727-6500.
Withholding or providing inaccurate health information to obtain treatment may lead to harm, including death.
What are the most serious side effects to monitor for while taking Ozempic?
If you experience a medical emergency, call 911 or seek immediate medical attention.
Serious side effects associated with Ozempic include:
- Thyroid C-Cell Tumors: While Ozempic's impact on human thyroid C-cell tumors remains uncertain, animal studies revealed an increase in thyroid C-cell tumors, including MTC. Ozempic is contraindicated for patients with a family history of MTC or MEN 2. Notify your provider if you notice neck lumps, swelling, hoarseness, difficulty swallowing, or shortness of breath, as these may indicate thyroid cancer.
- Acute Pancreatitis: Be vigilant for signs of acute pancreatitis, such as persistent severe abdominal pain, possibly radiating to the back, with or without vomiting.
- Diabetic Retinopathy Complications in Patients with Type 2 Diabetes: If you have type 2 diabetes, promptly inform your provider of any changes in vision.
- Never Share a Pen: Sharing Ozempic pens can lead to infections.
- Low Blood Sugar (Hypoglycemia): Ozempic can lower blood glucose, potentially causing low blood sugar in patients with type 2 diabetes using other glucose control medications. Monitor blood sugar levels and watch for signs of low blood sugar, including dizziness, blurred vision, mood changes, sweating, or rapid heartbeat.
- Acute Kidney Injury: In individuals with kidney issues, dehydration from diarrhea, nausea, and vomiting can worsen kidney problems. Ensure adequate hydration to reduce the risk of dehydration.
- Serious Allergic Reactions: Discontinue Ozempic immediately if you experience symptoms of a severe allergic reaction, such as facial swelling, severe rash, rapid heartbeat, breathing difficulties, or fainting.
- Acute Gallbladder Disease: Ozempic may lead to gallbladder problems, including gallstones. Some issues may require surgery. Inform your provider of upper stomach pain, yellowing of skin or eyes (jaundice), fever, or pale stools.
- Increase in Heart Rate: Notify your provider of a rapid resting heart rate.
- Suicidal Behavior and Ideation: Monitor your mental health for sudden changes in mood, behavior, thoughts, or feelings. If you experience new, worsening, or concerning mental changes, contact your healthcare provider promptly.
What are the most common side effects of Ozempic?
Common side effects of Ozempic include:
- Nausea
- Vomiting
- Diarrhea
- Stomach pain
- Constipation
If you experience adverse effects, please report them:
- Contact Novo Nordisk Inc. at 1-833-934-6891
- Contact FDA MedWatch at 1-800-FDA-1088 or visit www.fda.gov/medwatch
This information is not exhaustive. Refer to the full Prescribing Information for complete safety details.
Tirzepatide
Lowers A1C Levels
Helps you feel full faster, longer
Helps the body remove excess sugar from the blood
One subcutaneous injection weekly as directed by your JRNYS Healthcare provider
Common side effects with Tirzepatide include:
Redness & itching at the injection site
Loss of appetite
Tiredness
Nausea
Upset stomach
Diarrhea, or constipation may occur
Metformin®
The primary mechanism of metformin involves several actions within the body:
Decreased Glucose Production: Metformin reduces the amount of glucose produced by the liver. In people with type 2 diabetes, the liver often produces excess glucose, contributing to high blood sugar levels. By inhibiting this process, metformin helps lower fasting blood sugar levels.
Enhanced Insulin Sensitivity: Metformin improves the body's response to insulin, a hormone that helps cells absorb glucose from the bloodstream. In individuals with insulin resistance (a common feature of type 2 diabetes), cells do not respond well to insulin, leading to elevated blood sugar levels. Metformin enhances insulin sensitivity, allowing cells to utilize insulin more effectively.
Decreased Intestinal Glucose Absorption: Metformin reduces the absorption of glucose from the intestines after eating, leading to lower post-meal blood sugar levels.
Promotion of Weight Loss: Metformin can help some people with type 2 diabetes lose weight or prevent weight gain. It may contribute to a feeling of fullness and reduce food intake in some individuals.
Blood Sugar Control: Metformin is highly effective in lowering and controlling blood sugar levels, especially fasting blood sugar. By regulating glucose production and improving insulin sensitivity, it helps individuals with type 2 diabetes maintain stable blood sugar levels.
Weight Management: Metformin is associated with modest weight loss or prevention of weight gain in some individuals. This can be particularly beneficial for people with type 2 diabetes who are overweight or obese.
Cardiovascular Health: Some studies suggest that metformin may have cardiovascular benefits, such as improving lipid profiles and reducing the risk of heart-related complications in people with diabetes.
Lower Risk of Certain Health Complications: Properly managed blood sugar levels with metformin can lower the risk of diabetes-related complications, including kidney disease, nerve damage, and eye problems.
Polycystic Ovary Syndrome (PCOS) Management: Metformin is often used to manage insulin resistance in women with PCOS, helping regulate menstrual cycles and improve fertility.
While it is generally considered safe and effective, like any medication, it can cause side effects in some individuals. Common side effects of metformin include:
Gastrointestinal Distress: One of the most common side effects is gastrointestinal upset, including diarrhea, nausea, vomiting, and abdominal discomfort. These symptoms often occur at the beginning of treatment and may subside over time.
Loss of Appetite: Some individuals may experience a reduced appetite or feelings of fullness.
Taste Disturbances: Metformin can cause a metallic taste in the mouth or a lack of taste sensation.
Lactic Acidosis (Rare): Although rare, metformin can potentially lead to a serious condition called lactic acidosis, characterized by the buildup of lactic acid in the bloodstream. This is more common in individuals with kidney or liver problems. Symptoms include difficulty breathing, muscle pain, sluggishness, and in severe cases, a drop in body temperature and heart rate. Anyone experiencing these symptoms should seek immediate medical attention.
Vitamin B12 Deficiency: Long-term use of metformin has been associated with a decrease in vitamin B12 absorption, potentially leading to a deficiency. Regular monitoring of vitamin B12 levels and supplementation if necessary is recommended.
Low Blood Sugar (Hypoglycemia) (in combination with other diabetes medications): Taking metformin in combination with other medications for diabetes can increase the risk of low blood sugar. Symptoms include shakiness, dizziness, sweating, irritability, confusion, and in severe cases, loss of consciousness.
Skin Reactions: Some individuals may experience mild skin reactions such as redness or itching.
It's important for individuals taking metformin to be aware of these potential side effects. If any side effects are experienced, it is crucial to inform a healthcare provider. Additionally, metformin should be used with caution in individuals with kidney or liver problems, as these organs play a role in the elimination of the medication from the body. Regular monitoring and dosage adjustments are typically done under medical supervision.
What are GLP-1s?
GLP-1s, or Glucagon-Like Peptide-1 agonists, are a class of medications designed to help manage blood sugar levels. These drugs mimic the action of GLP-1, a natural hormone in the body that helps regulate blood sugar levels by stimulating insulin secretion, slowing down digestion, and reducing appetite.
By mimicking this hormone, GLP-1s help lower blood sugar levels after meals, leading to better glycemic control. Additionally, they have been found to promote weight loss and may have cardiovascular benefits. GLP-1s are typically administered via injection and have become an important therapeutic option for individuals striving to better manage their diabetes and improve their overall health
Tirzepatide
Lowers A1C Levels
Helps you feel full faster, longer
Helps the body remove excess sugar from the blood
One subcutaneous injection weekly as directed by your JRNYS Healthcare provider
Common side effects with Tirzepatide include:
Redness & itching at the injection site
Loss of appetite
Tiredness
Nausea
Upset stomach
Diarrhea, or constipation may occur
Important safety information
Important Safety Information for Ozempic (semaglutide) injection
Caution: Risk of Thyroid C-Cell Tumors
In animal studies involving mice and rats, semaglutide (the active component in Ozempic and Wegovy) was associated with thyroid tumors, including thyroid cancer. It is uncertain whether Ozempic may lead to thyroid tumors or a specific thyroid cancer called medullary thyroid carcinoma (MTC) in humans. If you notice any neck lumps, swelling, hoarseness, difficulty swallowing, or shortness of breath, please inform your healthcare provider. These could be signs of thyroid cancer.
Do not use Ozempic if you or any family member has a history of medullary thyroid carcinoma (MTC) or a condition known as Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
What is the FDA-approved use of Ozempic?
Ozempic is a glucagon-like peptide-1 (GLP-1) receptor agonist used for:
- Enhancing glycemic control in patients with type 2 diabetes mellitus, alongside diet and exercise.
- Reducing the risk of major cardiovascular events in patients with type 2 diabetes mellitus and established cardiovascular disease.
Limitations of Use:
- Ozempic has not been studied in patients with a history of pancreatitis.
- Ozempic is not intended for treating type 1 diabetes mellitus.
- Your JRNYS-affiliated provider may suggest Ozempic for chronic weight management (obesity or overweight).
Who should avoid Ozempic?
Do not use Ozempic if:
- You or any family member has a history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
- You have known allergies to semaglutide (the active ingredient in Wegovy or Ozempic).
How should Ozempic be administered?
Ozempic can be taken with or without food. The pre-filled injector pen is self-administered as a subcutaneous injection in the stomach, thigh, or upper arm once a week on the same day each week.
Your JRNYS-affiliated provider will guide you on the treatment plan, which may include dose increases every four weeks.
Do not alter your dosing regimen or discontinue Ozempic without consulting your provider first.
What should I inform my JRNYS-affiliated provider before using Ozempic?
Ozempic can interact with certain medications. It's crucial to disclose all current medications, including prescription, over-the-counter drugs, vitamins, herbal supplements, and dietary supplements to your JRNYS-affiliated provider.
Some medications to be aware of include:
- Drugs for type 1 or type 2 diabetes, such as insulin or sulfonylureas (e.g., Amaryl or Glucotrol XL).
- Ozempic can delay gastric emptying, potentially affecting the absorption of orally taken medications. Your provider can advise on scheduling your medications.
Additionally, share your complete medical history with your provider, especially if you have a history of:
- Type 1 or type 2 diabetes
- Thyroid cancer
- Pancreatitis
- Kidney disease
- Diabetic retinopathy
- Depression
- Suicidal thoughts or behavior
Notify your provider if you are pregnant, planning to become pregnant, or breastfeeding.
If pregnant: Ozempic should not be used during pregnancy. Animal studies suggest potential risks to the unborn baby from Ozempic exposure during pregnancy. Weight loss during pregnancy is not beneficial and may harm the baby.
If of reproductive potential: Discontinue Ozempic at least two months before planned pregnancy, as the drug may persist in the bloodstream.
If breastfeeding: Ozempic was detected in the milk of lactating rats. Inform your JRNYS-affiliated provider if you are breastfeeding before starting Ozempic.
Pregnancy registry: A pregnancy exposure registry monitors outcomes in women exposed to semaglutide (the active ingredient in Ozempic and Ozempic) during pregnancy.
Pregnant women exposed to semaglutide and healthcare providers can contact Novo Nordisk at 1-800-727-6500.
Withholding or providing inaccurate health information to obtain treatment may lead to harm, including death.
What are the most serious side effects to monitor for while taking Ozempic?
If you experience a medical emergency, call 911 or seek immediate medical attention.
Serious side effects associated with Ozempic include:
- Thyroid C-Cell Tumors: While Ozempic's impact on human thyroid C-cell tumors remains uncertain, animal studies revealed an increase in thyroid C-cell tumors, including MTC. Ozempic is contraindicated for patients with a family history of MTC or MEN 2. Notify your provider if you notice neck lumps, swelling, hoarseness, difficulty swallowing, or shortness of breath, as these may indicate thyroid cancer.
- Acute Pancreatitis: Be vigilant for signs of acute pancreatitis, such as persistent severe abdominal pain, possibly radiating to the back, with or without vomiting.
- Diabetic Retinopathy Complications in Patients with Type 2 Diabetes: If you have type 2 diabetes, promptly inform your provider of any changes in vision.
- Never Share a Pen: Sharing Ozempic pens can lead to infections.
- Low Blood Sugar (Hypoglycemia): Ozempic can lower blood glucose, potentially causing low blood sugar in patients with type 2 diabetes using other glucose control medications. Monitor blood sugar levels and watch for signs of low blood sugar, including dizziness, blurred vision, mood changes, sweating, or rapid heartbeat.
- Acute Kidney Injury: In individuals with kidney issues, dehydration from diarrhea, nausea, and vomiting can worsen kidney problems. Ensure adequate hydration to reduce the risk of dehydration.
- Serious Allergic Reactions: Discontinue Ozempic immediately if you experience symptoms of a severe allergic reaction, such as facial swelling, severe rash, rapid heartbeat, breathing difficulties, or fainting.
- Acute Gallbladder Disease: Ozempic may lead to gallbladder problems, including gallstones. Some issues may require surgery. Inform your provider of upper stomach pain, yellowing of skin or eyes (jaundice), fever, or pale stools.
- Increase in Heart Rate: Notify your provider of a rapid resting heart rate.
- Suicidal Behavior and Ideation: Monitor your mental health for sudden changes in mood, behavior, thoughts, or feelings. If you experience new, worsening, or concerning mental changes, contact your healthcare provider promptly.
What are the most common side effects of Ozempic?
Common side effects of Ozempic include:
- Nausea
- Vomiting
- Diarrhea
- Stomach pain
- Constipation
If you experience adverse effects, please report them:
- Contact Novo Nordisk Inc. at 1-833-934-6891
- Contact FDA MedWatch at 1-800-FDA-1088 or visit www.fda.gov/medwatch
This information is not exhaustive. Refer to the full Prescribing Information for complete safety details.
Semaglutide
- Lowers A1C Levels
- Helps you feel full faster, longer
- Improves the way your body responds to sugars
- Semaglutide is not FDA-approved for weight loss, but may be prescribed if a provider deems it appropriate*
- 24/7 Provider & Nursing support
- Medications, syringes, alcohol swabs
- Weight monitoring via app
- Shipping delivered to your door
- Optional nutritional counseling
Semaglutide is typically administered as a once-weekly subcutaneous injection, meaning it is injected just under the skin, usually in the abdomen, thigh, or upper arm. It's important to rotate the injection site each week to avoid irritation. Always follow the dosing instructions provided by your healthcare provider, starting with a lower dose and gradually increasing based on your body's response. Be sure to use a clean needle for each injection and dispose of it safely. If you miss a dose, take it as soon as you remember, unless it's less than 48 hours before your next scheduled dose. Never double up on doses. For optimal results, use semaglutide in combination with a healthy diet and regular exercise
Common side effects of semaglutide may include nausea, vomiting, diarrhea, constipation, and abdominal pain, especially when starting treatment. Other possible side effects include fatigue, dizziness, and decreased appetite. In rare cases, semaglutide can cause more serious side effects like pancreatitis, gallbladder issues, or allergic reactions. If you experience severe abdominal pain, difficulty breathing, or swelling of the face or throat, seek medical attention immediately. Always consult your healthcare provider about any side effects or concerns you may have.
* This page has been medically reviewed
* Actual price to customer will depend on product and subscription plan purchase.
Important safety information
Important Safety Information for Ozempic (semaglutide) injection
Caution: Risk of Thyroid C-Cell Tumors
In animal studies involving mice and rats, semaglutide (the active component in Ozempic and Wegovy) was associated with thyroid tumors, including thyroid cancer. It is uncertain whether Ozempic may lead to thyroid tumors or a specific thyroid cancer called medullary thyroid carcinoma (MTC) in humans. If you notice any neck lumps, swelling, hoarseness, difficulty swallowing, or shortness of breath, please inform your healthcare provider. These could be signs of thyroid cancer.
Do not use Ozempic if you or any family member has a history of medullary thyroid carcinoma (MTC) or a condition known as Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
What is the FDA-approved use of Ozempic?
Ozempic is a glucagon-like peptide-1 (GLP-1) receptor agonist used for:
- Enhancing glycemic control in patients with type 2 diabetes mellitus, alongside diet and exercise.
- Reducing the risk of major cardiovascular events in patients with type 2 diabetes mellitus and established cardiovascular disease.
Limitations of Use:
- Ozempic has not been studied in patients with a history of pancreatitis.
- Ozempic is not intended for treating type 1 diabetes mellitus.
- Your JRNYS-affiliated provider may suggest Ozempic for chronic weight management (obesity or overweight).
Who should avoid Ozempic?
Do not use Ozempic if:
- You or any family member has a history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
- You have known allergies to semaglutide (the active ingredient in Wegovy or Ozempic).
How should Ozempic be administered?
Ozempic can be taken with or without food. The pre-filled injector pen is self-administered as a subcutaneous injection in the stomach, thigh, or upper arm once a week on the same day each week.
Your JRNYS-affiliated provider will guide you on the treatment plan, which may include dose increases every four weeks.
Do not alter your dosing regimen or discontinue Ozempic without consulting your provider first.
What should I inform my JRNYS-affiliated provider before using Ozempic?
Ozempic can interact with certain medications. It's crucial to disclose all current medications, including prescription, over-the-counter drugs, vitamins, herbal supplements, and dietary supplements to your JRNYS-affiliated provider.
Some medications to be aware of include:
- Drugs for type 1 or type 2 diabetes, such as insulin or sulfonylureas (e.g., Amaryl or Glucotrol XL).
- Ozempic can delay gastric emptying, potentially affecting the absorption of orally taken medications. Your provider can advise on scheduling your medications.
Additionally, share your complete medical history with your provider, especially if you have a history of:
- Type 1 or type 2 diabetes
- Thyroid cancer
- Pancreatitis
- Kidney disease
- Diabetic retinopathy
- Depression
- Suicidal thoughts or behavior
Notify your provider if you are pregnant, planning to become pregnant, or breastfeeding.
If pregnant: Ozempic should not be used during pregnancy. Animal studies suggest potential risks to the unborn baby from Ozempic exposure during pregnancy. Weight loss during pregnancy is not beneficial and may harm the baby.
If of reproductive potential: Discontinue Ozempic at least two months before planned pregnancy, as the drug may persist in the bloodstream.
If breastfeeding: Ozempic was detected in the milk of lactating rats. Inform your JRNYS-affiliated provider if you are breastfeeding before starting Ozempic.
Pregnancy registry: A pregnancy exposure registry monitors outcomes in women exposed to semaglutide (the active ingredient in Ozempic and Ozempic) during pregnancy.
Pregnant women exposed to semaglutide and healthcare providers can contact Novo Nordisk at 1-800-727-6500.
Withholding or providing inaccurate health information to obtain treatment may lead to harm, including death.
What are the most serious side effects to monitor for while taking Ozempic?
If you experience a medical emergency, call 911 or seek immediate medical attention.
Serious side effects associated with Ozempic include:
- Thyroid C-Cell Tumors: While Ozempic's impact on human thyroid C-cell tumors remains uncertain, animal studies revealed an increase in thyroid C-cell tumors, including MTC. Ozempic is contraindicated for patients with a family history of MTC or MEN 2. Notify your provider if you notice neck lumps, swelling, hoarseness, difficulty swallowing, or shortness of breath, as these may indicate thyroid cancer.
- Acute Pancreatitis: Be vigilant for signs of acute pancreatitis, such as persistent severe abdominal pain, possibly radiating to the back, with or without vomiting.
- Diabetic Retinopathy Complications in Patients with Type 2 Diabetes: If you have type 2 diabetes, promptly inform your provider of any changes in vision.
- Never Share a Pen: Sharing Ozempic pens can lead to infections.
- Low Blood Sugar (Hypoglycemia): Ozempic can lower blood glucose, potentially causing low blood sugar in patients with type 2 diabetes using other glucose control medications. Monitor blood sugar levels and watch for signs of low blood sugar, including dizziness, blurred vision, mood changes, sweating, or rapid heartbeat.
- Acute Kidney Injury: In individuals with kidney issues, dehydration from diarrhea, nausea, and vomiting can worsen kidney problems. Ensure adequate hydration to reduce the risk of dehydration.
- Serious Allergic Reactions: Discontinue Ozempic immediately if you experience symptoms of a severe allergic reaction, such as facial swelling, severe rash, rapid heartbeat, breathing difficulties, or fainting.
- Acute Gallbladder Disease: Ozempic may lead to gallbladder problems, including gallstones. Some issues may require surgery. Inform your provider of upper stomach pain, yellowing of skin or eyes (jaundice), fever, or pale stools.
- Increase in Heart Rate: Notify your provider of a rapid resting heart rate.
- Suicidal Behavior and Ideation: Monitor your mental health for sudden changes in mood, behavior, thoughts, or feelings. If you experience new, worsening, or concerning mental changes, contact your healthcare provider promptly.
What are the most common side effects of Ozempic?
Common side effects of Ozempic include:
- Nausea
- Vomiting
- Diarrhea
- Stomach pain
- Constipation
If you experience adverse effects, please report them:
- Contact Novo Nordisk Inc. at 1-833-934-6891
- Contact FDA MedWatch at 1-800-FDA-1088 or visit www.fda.gov/medwatch
This information is not exhaustive. Refer to the full Prescribing Information for complete safety details.
How it works
We help you lose weight with revolutionary medication, concierge medical support, nutritional coach support, optional meal planning & more
Provide your health background and weight loss objectives to your JRNYS-affiliated provider.
Provide your health background and weight loss objectives to your JRNYS-affiliated provider. Provide your health background and weight loss objectives to your JRNYS-affiliated provider.
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Real people, real success.
Jen
Lost 43lbs
Audrey
Lost 53lbs
Kevin
Lost 60lbs
Stef
Lost 37lbs
Preston
Lost 28lbs
Jess
Lost 22lbs
Catherine
Lost 10 lbs
Jen
Lost 43lbs
"I was never petite and was considered overweight by age 14. The challenge intensified after having three children and navigating the pandemic, leading to a significant struggle with weight loss. My turning point came with JRNYS, which reignited my internal motivation. I was prescribed Mounjaro (the same drug as Zepbound/Tirzepatide), and the results have been transformative—I've lost over 40 pounds in the past seven months. This journey feels like just the beginning. I'm now enthusiastic about going to the gym and am on a path to completely revitalize my life."
Audrey
Lost 53lbs
"Initially, I weighed 185 pounds at a height of 5 feet 7 inches, and I was struggling with pre-diabetes and PCOS, urgently seeking effective solutions. Within a week of consulting my JRNYS doctors, they managed to get GLP-1 receptor agonists prescribed for me. Since embarking on this treatment program, I have experienced significant progress, losing close to 60 pounds to date. This journey has not only been about weight loss but also about regaining control over my health and confronting the challenges posed by pre-diabetes and PCOS head-on."
Kevin
Lost 60lbs
“My wife gave me shit for years because my core wasn’t strong enough to stand on a paddle board. Now that I’ve lost 60lbs and strengthened my core I look great but still can’t stand on a paddle board”.
Stef
Lost 37lbs
"After the pandemic, I found myself at the heaviest weight I'd ever been, nearly 160 pounds. The impact of COVID-19 was severe, leaving me with fatigue that lasted almost three months. Determined to make a change, I committed to regular exercise and joined the JRNYS program. My doctors prescribed me Mounjaro (also known as Tirzepatide or Zepbound) and it worked within the first week. This combination of physical activity and structured guidance transformed my life. Remarkably, I managed to reduce my weight to 123 pounds and fit into a size 2, a milestone I had never achieved in my adult life. This journey was not just about losing weight; it was about overcoming unprecedented challenges and reaching a state of health and confidence I never thought possible."
Preston
Lost 28lbs
Throughout my life, I never really focused on eating healthily or maintaining a fit lifestyle, and this started to take a toll on me in my 30s. I found myself unable to play sports with the same vigor and felt a general sense of slowing down. However, that all changed with the JRNYS program. Surprisingly, without any significant changes to my lifestyle other than the program, I managed to lose close to 30 pounds. This weight loss has given me a lot more energy, rejuvenating my ability to enjoy sports and activities with a renewed zest.
Jess
Lost 22lbs
“I absolutely lost the fight with my weight in my 40’s after two kids and a stressful job. Despite regular exercise and ongoing dieting I was carrying 20lbs I could not shed. After 3 months on Mounjaro, I lost 22 lbs. All of the muscle I’d built from my workouts finally started showing and I’ve never felt so confident about my body. Thank you to the JRNYS team!”
Catherine
Lost 10 lbs
Being diagnosed with PCOS was a challenging chapter in my life. It led to an unexpected weight gain of over 30 pounds, along with acne, hair loss, insulin resistance, and relentless fatigue. But the tide turned when I started working with JRNYS and taking Ozempic. In just the first two weeks, I lost 10 pounds, a change that felt nothing short of miraculous. Gradually, I returned to my normal weight, feeling a sense of relief and normalcy that had seemed out of reach. This journey wasn’t just about weight loss; it was about regaining control and balance in my life.